Sulforaphane in Broccoli: The Green Chemoprevention! Role in Cancer Prevention and Therapy

Isothicyanates present in cruciferous vegetables are known to exhibit chemoprevention by various mechanisms. Presently, there is growing evidence that a ph

Jos de Mul, Bibi van den Berg

2011 · https://doi.org/10.4103/jomfp.JOMFP_126_19

Abstract

Isothicyanates present in cruciferous vegetables are known to exhibit chemoprevention by various mechanisms. Presently, there is growing evidence that a phytochemical compound known as sulforaphane in these green leafy vegetables is found to be effective in preventing and treating various cancers such as prostate cancer, breast cancer, colon cancer, skin, urinary bladder and oral cancers. This component is naturally present in the broccoli sprouts, kale, cabbage, cauliflower and garden cress and is available as a commercial supplementary pill called Broccoli extract. Availability of many bioactive substances such as vitamins, polyphenols, sulfides, glucosinolates and antioxidants makes broccoli consumption important in daily diet regularly. Researchers have named it as “Green chemoprevention.” It is easily affordable and more cost-effective than the traditional chemopreventive drugs. Results from the epidemiological and experimental studies have emphasized the role of sulforophane as a complementary or alternative chemopreventive agent.

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Jos de Mul; Bibi van den Berg (2011). Sulforaphane in Broccoli: The Green Chemoprevention! Role in Cancer Prevention and Therapy. Journal of Oral and Maxillofacial Pathology. https://doi.org/10.4103/jomfp.JOMFP_126_19 Licensed under Creative Commons Attribution NC SA (https://creativecommons.org/licenses/by-nc-sa/4.0/). Hosted by EVEC Athens (microgreens.org.gr). No changes were made to this article. Provided as-is, without warranties. EVEC Athens is not affiliated with, and this copy is not endorsed by, the authors or the publisher.

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